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KMID : 0371620080230020151
Journal of Wonkwang Medical Science
2008 Volume.23 No. 2 p.151 ~ p.155
Small Bowel Perforation caused by Neutropenic Enterocolitis combined with Aspergillus Infection in a Patient with Acute Lymphocytic Leukemia
Kang Dong-Baek

Im Tae-Su
Park Won-Cheol
Yun Ki-Jung
Lee Jeong-Kyun
Abstract
Though advancesin imumosuppressive therapy or chemotherapy which have lead to increased survival of leukemia and transplant patient, but the risk of infectious complication has been increasing. Neutropenic enterocolitis is a life threatening complication of chemotherapy for malignancies such as leukemia or lymphoma. Symptoms of neutropenic enterocolitis are nonspecific and it may rapidly lead to intestinal peforation. Aspergilus infection could involve the gastrointestinal tract as a result of neutropenia and mucosal injury after imumosuppressive therapy, chemoetherapy, or antibiotics use, but rarely reported a small bowel perforation combined aspergillus and neutropenic enterocolitis. We present a rare case of ileal perforation caused by neutropenic enterocolitis combined with aspergillus infection during chemotherapy for acute lymphocytic leukemia with a review of the literature.
KEYWORD
Neutropenic enterocolitis, Aspergillus infection, Small bowel perforation
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