KMID : 0371620080230020151
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Journal of Wonkwang Medical Science 2008 Volume.23 No. 2 p.151 ~ p.155
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Small Bowel Perforation caused by Neutropenic Enterocolitis combined with Aspergillus Infection in a Patient with Acute Lymphocytic Leukemia
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Kang Dong-Baek
Im Tae-Su Park Won-Cheol Yun Ki-Jung Lee Jeong-Kyun
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Abstract
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Though advancesin imumosuppressive therapy or chemotherapy which have lead to increased survival of leukemia and transplant patient, but the risk of infectious complication has been increasing. Neutropenic enterocolitis is a life threatening complication of chemotherapy for malignancies such as leukemia or lymphoma. Symptoms of neutropenic enterocolitis are nonspecific and it may rapidly lead to intestinal peforation. Aspergilus infection could involve the gastrointestinal tract as a result of neutropenia and mucosal injury after imumosuppressive therapy, chemoetherapy, or antibiotics use, but rarely reported a small bowel perforation combined aspergillus and neutropenic enterocolitis. We present a rare case of ileal perforation caused by neutropenic enterocolitis combined with aspergillus infection during chemotherapy for acute lymphocytic leukemia with a review of the literature.
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KEYWORD
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Neutropenic enterocolitis, Aspergillus infection, Small bowel perforation
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